6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione

CAS: 5617-70-9

Ref. TR-D471415

Product Information

• Name: 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione
• Synonyms: 1,1-Cyclopropanedicarboxylic Acid Cyclic Isopropylidene Ester, 1,1-Cyclopropanedicarboxylic Acid Cyclic 1-Methylethylidene Ester, 2,2-Propanediol Cyclic 1,1-Cyclopropanedicarboxylate, 6,6-Dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione
• Brand: TRC

Description

Applications 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).
References Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012)

Chemical properties

• Molecular weight: 170.16
• Formula: C₈H₁₀O₄
• Color/Form: Neat
• InChI: InChI=1S/C8H10O4/c1-7(2)11-5(9)8(3-4-8)6(10)12-7/h3-4H2,1-2H3
• InChI key: InChIKey=AXJVPXNVESYGDT-UHFFFAOYSA-N
• SMILES: CC1(C)OC(=O)C2(CC2)C(=O)O1