(3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol-d6 (Contain up to 15% δ25 isomer)

CAS: 64284-64-6

Ref. TR-D471727

Product Information

• Name: (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol-d6 (Contain up to 15% δ25 isomer)
• Synonyms: 4,4-Dimethyl-5a-cholesta-8,14,24-trien-3ß-ol-d6, FF-MAS-d6, Follicular Fluid Meiosis-activating Sterol-d6, (3b,5a)-4,4-Dimethylcholesta-8,14,24-trien-3-ol, (3beta,5alpha)-4,4-dimethyl-Cholesta-8,14,24-trien-3-ol, 4,4-Dimethyl-5α-cholesta-8,14,24-trien-3β-ol, Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3beta,5alpha)-, Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3β,5α)-, Ff-Mas, Follicular fluid meiosis-activating sterol, (3beta,5alpha)-4,4-Dimethylcholesta-8,14,24-trien-3-ol

Description

Applications Labelled (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol, a follicular fluid meiosis-activating sterol (FF-MAS); a factor present in the pre-ovulatory follicle during the time of oocyte maturation. (3β,5α)-4,4-Dimethylcholesta-8,14,24-trien-3-ol has been shown to protect young oocytes from precocious chromatid separation as well as protecting aged oocytes from predivision during maturation.
References Cao, X. et al.: Biol. Reprod., 71, 1807 (2004); Cukurcam, S. et al.: Hum. Reprod., 22, 815 (2007); Bivens, C.L.M. et al.: Hum. Reprod. 19, 2340 (2004);

• Brand: TRC

Chemical properties

• Molecular weight: 416.71
• Formula: C₂₉H₄₀D₆O
• Color/Form: Neat
• InChI: InChI=1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1/i4D3,5D3
• InChI key: InChIKey=LFQXEZVYNCBVDO-NNUIBIGGSA-N
• SMILES: [2H]C([2H])([2H])C1(C([2H])([2H])[2H])[C@@H](O)CC[C@]2(C)C3=C(CC[C@@H]12)C1=CC[C@H]([C@H](C)CCC=C(C)C)[C@@]1(C)CC3