rac-Alpha-[2-(Dimethylamino)ethyl]-3-thiophenemethanol

CAS: 116817-84-6

Ref. TR-D471825

Product Information

• Name: rac-Alpha-[2-(Dimethylamino)ethyl]-3-thiophenemethanol
• Synonyms: alpha-[2-(Dimethylamino)ethyl]-3-thiophenemethanol, (S)-(+)-N,N-dimethyl-3-hydroxy-(2-thienyl)-propanamine, (S)-1-b-Hydroxy-1-(2-thienyl)-3-dimethylaminopropane, 3-Thiophenemethanol, A-[2-(Dimethylamino)Ethyl]-, 3-Thiophenemethanol, A-[2-(Dimethylamino)Ethyl]-(9Ci), S(+)-N,N-Dimethyl-3-Hydroxy-3-(2-Thienyl)-1-Propanamine, S-(-)-N,N-Dimethyl-3-Hydroxy-2-Thienylpropanamine, α-[2-(Dimethylamino)ethyl]-3-thiophenemethanol
• CAS: 116817-84-6

Description

Applications rac-α-[2-(Dimethylamino)ethyl]-3-thiophenemethanol is an intermediate in the synthesis of rac Duloxetine 3-Thiophene Isomer (D721025). rac Duloxetine 3-Thiophene Isomer Hydrochloride is an isomeric impurity of the antidepressant Duloxetine Hydrochloride (D721000).
References Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 185.29
• Formula: C₉H₁₅NOS
• Color/Form: Neat
• InChI: InChI=1S/C9H15NOS/c1-10(2)5-3-9(11)8-4-6-12-7-8/h4,6-7,9,11H,3,5H2,1-2H3
• InChI key: InChIKey=HKVIPLMMUMBSKB-UHFFFAOYSA-N
• SMILES: CN(C)CCC(O)c1ccsc1