2,4-Dinitrophenyl 2-Deoxy-2-fluoro-beta-D-galactoside
CAS: 143716-62-5
Ref. TR-D480065
| 10mg | Discontinued | ||
| 100mg | Discontinued |
Product Information
Name:
2,4-Dinitrophenyl 2-Deoxy-2-fluoro-beta-D-galactoside
Synonyms:
- 2,4-Dinitrophenyl 2-Deoxy-2-fluoro-β-D-galactopyranoside
- 2',4'-Dinitrophenyl 2-deoxy-2-fluoro-beta-D-galactopyranoside
- Dinitroph-dfgp
- beta-D-Galactopyranoside, 2,4-dinitrophenyl 2-deoxy-2-fluoro-
- 2',4'-Dinitrophenyl 2-deoxy-2-fluorogalactopyranoside
Description:
Applications Fluorinated and deoxygenated glycosides as mechanistic probes of Escherichia coli (lacZ) β-galactosidase. By use of the slow substrate 2,4-dinitrophenyl-2-deoxy-2-fluoro-β-D-galactopyranoside, a glycosyl enzyme intermediate has been trapped on the enzyme. Glu-268 was identified as the catalytic nucleophile of human lysosomal β-galactosidase precursor.
References Withers, S., et al.: J. Biol. Chem., 263, 7929 (1988), D'Agrosa, R., et al.: Biochem. J., 285, 833 (1992),
Notice:
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Brand:
TRC
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Chemical properties
Molecular weight:
348.24
Formula:
C12H13FN2O9
Color/Form:
Off-White to Pale Yellow Solid
SMILES:
O=[N+]([O-])c1ccc(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2F)c([N+](=O)[O-])c1
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