N-[(1,1-Dimethylethoxy)carbonyl]glycyl-4,4-difluoro-L-prolinamide
CAS: 1448440-48-9
Ref. TR-D489140
100mg | 1,060.00 € |
Product Information
- tert-butyl N-[2-[(2S)-2-carbamoyl-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamate
Applications N-[(1,1-Dimethylethoxy)carbonyl]glycyl-4,4-difluoro-L-prolinamide is a reagent in the synthesis of (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide (UAMC1110) (S687910) which is a useful research chemical and a fibroblast activation protein inhibitor displaying low nanomolar inhibitory potency and high selectivity against related dipeptidyl peptidases.
References De D., et al.: ACS Med. Chem., 10, 1173 (2019); Simon, P., et al.: ACS Chem. Biol., 13, 3333 (2018); De D., et al.: ACS Med. Chem. Lett., 10, 1173 (2019)
Chemical properties
Technical inquiry about: TR-D489140 N-[(1,1-Dimethylethoxy)carbonyl]glycyl-4,4-difluoro-L-prolinamide
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