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5-O-demethyl-28-hydroxy-Avermectin A1a
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5-O-demethyl-28-hydroxy-Avermectin A1a

CAS: 96722-46-2

Ref. TR-D722000

1mg
244.00 €
5mg
1,057.00 €
10mg
1,658.00 €
Estimated delivery in United States, on Friday 20 Dec 2024

Product Information

Name:
5-O-demethyl-28-hydroxy-Avermectin A1a
Controlled Product
Synonyms:
  • Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-
  • 3,2'-[2H]pyran]
  • avermectin A1a deriv.
  • 28-Hydroxyavermectin B1a
  • 8alpha-hydroxy-avermectib B1a
Description:

Applications 5-O-demethyl-28-hydroxy-Avermectin A1a is a derivatie of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin. An invitro inhibitor of SARS-CoV-2/ Covid-19.
References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
889.08
Formula:
C48H72O15
Color/Form:
Neat
InChI:
InChI=1S/C48H72O15/c1-11-24(2)42-27(5)17-18-47(63-42)23-32-20-31(62-47)16-15-26(4)41(59-38-22-36(55-10)43(30(8)57-38)60-37-21-35(54-9)40(50)29(7)56-37)25(3)13-12-14-33-45(51)61-44-39(49)28(6)19-34(46(52)58-32)48(33,44)53/h12-15,17-19,24-25,27,29-32,34-45,49-51,53H,11,16,20-23H2,1-10H3/b13-12+,26-15+,33-14-/t24-,25+,27+,29+,30+,31-,32+,34+,35+,36+,37+,38+,39-,40+,41+,42-,43+,44-,45?,47-,48-/m1/s1
InChI key:
InChIKey=ORIHAMOZRDYFCM-MLBVANKNSA-N
SMILES:
CC[C@H](C)[C@H]1O[C@]2(C=C[C@@H]1C)C[C@@H]1CC(C/C=C(\C)[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)/C=C/C=C3\C(O)O[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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