Eflornithine-d6 Hydrochloride Monohydrate

CAS: 96020-91-6

Ref. TR-E436002

Product Information

• Name: Eflornithine-d6 Hydrochloride Monohydrate
• Synonyms: 2-(Difluoromethyl)-DL-ornithine-d6 Hydrochloride Hydrate, 2-(Difluoromethyl)ornithine-d6, DFMO-d6, DL-2-(Difluoromethyl)ornithine-d6, DL-α-(Difluoromethyl)ornithine-d6, Elfornithine-d6, MDL 71782-d6, MDL 71782A-d6, Ornidyl-d6, RFI 71782-d6, RMI 71782-d6, α,δ-Diamino-α-(difluoromethyl)valeric Acid-d6, α-(Difluoromethyl)-DL-ornithine-d6, α-(Difluoromethyl)ornithine-d6, 2,5-Diamino-2-(Difluoromethyl)Pentanoic Acid, 2,5-Diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride, <span class="text-smallcaps">DL</span>-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate, DFMO Eflornithine, DMFO HCl, Eflornithine hydrochloride monohydrate, H-alpha-Difluoro-Me-DL-Orn-OH.HCl.H2O, Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1), Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
• CAS: 96020-91-6

Description

Applications Labelled Eflornithine. Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
References Bacchi, C.J., et al.: Science, 210, 332 (1980), Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981), Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 242.682
• Formula: C₆H₉D₆ClF₂N₂O₃
• Color/Form: White to Light Yellow Solid
• InChI: InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2/i1D2,2D2,3D2
• InChI key: InChIKey=FJPAMFNRCFEGSD-HRTLFCCJSA-N
• SMILES: Cl.O.[2H]C([2H])(N)C([2H])([2H])C([2H])([2H])C(N)(C(=O)O)C(F)F