5-epi Emtricitabine Carboxylic Acid
Ref. TR-E524985
25mg | 3,618.00 € |
Product Information
- (2R,5R)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid
Applications 5-epi Emtricitabine Carboxylic Acid is an impurity of 5-epi Emtricitabine (E524980); an epimer of Emtricitabine (E525000) which is a nucleoside reverse transcriptase inhibitor approved for treatment of HIV-1. Emtricitabine also has antagonistic activity against the hepatitis B virus.
References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993); Lim, S. et al.: Arch. Intern. Med., 166, 49 (2006); Smith, K., et al.: AIDS, 23, 1547 (2009)
Chemical properties
Technical inquiry about: TR-E524985 5-epi Emtricitabine Carboxylic Acid
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