(5α)-4,5-Epoxy-8,14-dihydroxy-3-methoxymorphinan-6-one
CAS: 1649937-50-7
Ref. TR-E589365
| 1mg | Discontinued | ||
| 5mg | Discontinued | ||
| 10mg | Discontinued |
Product Information
Name:
(5α)-4,5-Epoxy-8,14-dihydroxy-3-methoxymorphinan-6-one
CAS:
Description:
Applications (5α)-4,5-epoxy-8,14-dihydroxy-3-methoxymorphinan-6-one is an intermediate in the synthesis of N-Allyldihydro-8,10,14-trihydroxynormorphinone (A549610), an impurity of Naloxone (HCl salt, N285000) which is a specific opioid antagonist and narcotic antagonist.
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)
Notice:
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Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
317.34
Formula:
C17H19NO5
Color/Form:
Brown Solid
InChI:
InChI=1S/C17H19NO5/c1-22-10-3-2-8-6-11-17(21)12(20)7-9(19)15-16(17,4-5-18-11)13(8)14(10)23-15/h2-3,11-12,15,18,20-21H,4-7H2,1H3/t11-,12?,15+,16+,17+/m1/s1
InChI key:
InChIKey=ALSYDNVZYDKTLU-ZJDSXEOWSA-N
SMILES:
COc1ccc2c3c1O[C@H]1C(=O)CC(O)[C@@]4(O)[C@@H](C2)NCC[C@]314
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