Estradiol 3-[N,N-Bis(2-chloroethyl)carbamate]

CAS: 2998-57-4

Ref. TR-E888075

Product Information

• Name: Estradiol 3-[N,N-Bis(2-chloroethyl)carbamate]
• Synonyms: Estramustine, (17Beta)-17-Hydroxyestra-1,3,5(10)-Trien-3-Yl Bis(2-Chloroethyl)Carbamate, 17-Hydroxyestra-1,3,5(10)-Trien-3-Yl Bis(2-Chloroethyl)Carbamate, 17β-Estradiol 3-[bis(2-chloroethyl)carbamate], 2998-57-4, Carbamic acid, bis(2-chloroethyl)-, 17β-hydroxyestra-1,3,5(10)-trien-3-yl ester, Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-[bis(2-chloroethyl)carbamate], Estracty, Estradiol 3-[N,N-bis(2-chloroethyl)carbamate], Estradiol, 3-[bis(2-chloroethyl)carbamate], Estramustin, Estramustina, Leo 275, Nsc 89201, Ro 22-2296/000, β-Estradiol 3-[N,N-bis(2-chloroethyl)carbamate]

Description

Applications Estradiol 3-[N,N-Bis(2-chloroethyl)carbamate] is used treatment of breast cancer. Also used in the treatment of prostate cancer.
References Hilavac, V. et al.: Pharmacogenom., 14, 515 (2013);

• Brand: TRC

Chemical properties

• Molecular weight: 440.40
• Formula: C₂₃H₃₁Cl₂NO₃
• Color/Form: White
• InChI: InChI=1S/C23H31Cl2NO3/c1-23-9-8-18-17-5-3-16(29-22(28)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)27/h3,5,14,18-21,27H,2,4,6-13H2,1H3/t18-,19-,20+,21+,23+/m1/s1
• InChI key: InChIKey=FRPJXPJMRWBBIH-RBRWEJTLSA-N
• SMILES: C[C@]12CC[C@@H]3c4ccc(OC(=O)N(CCCl)CCCl)cc4CC[C@H]3[C@@H]1CC[C@@H]2O