b-Estradiol-6-one 6-(O-carboxymethyloxime)

CAS: 35048-47-6

Ref. TR-E888080

Product Information

• Name: b-Estradiol-6-one 6-(O-carboxymethyloxime)
• Synonyms: 2-[[[(17ß)-3,17-Dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]acetic Acid, Estrane Acetic Acid Deriv., 17ß-Estradiol 6-(O-carboxymethyl)oxime, 6-Oxo-17ß-estradiol 6-[O-(carboxymethyl)oxime], 6-Oxoestradiol (carboxymethyl)oxime, Estradiol 6-(O-carboxymethyl)oxime, Estradiol 6-carboxymethyloxime, Estrone 6-(O-carboxymethyl)oxime, ({[(6E,8ξ,9ξ,14ξ,17β)-3,17-dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino}oxy)acetic acid, 17β-Estradiol 6-(O-carboxymethyl)oxime, 2-[[[(17β)-3,17-Dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]acetic acid, 6-Oxo-17β-estradiol 6-[O-(carboxymethyl)oxime], 6-ketoestradiol 6-(O-carboxymethyl)-*oxime, Acetic acid, 2-[[[(17β)-3,17-dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]-, Acetic acid, [[[(17β)-3,17-dihydroxyestra-1,3,5(10)-trien-6-ylidene]amino]oxy]-, Estrane, acetic acid deriv., beta-Estradiol-6-one 6-(O-carboxymethyloxime)

Description

Applications β-Estradiol-6-one 6-(O-carboxymethyloxime) was shown to exhibit regulatory activities towards the expression of leptin, a protein hormone that coordinate appetite/hunger and metabolism.β-Estradiol-6-one 6-(O-carboxymethyloxime) was shown to control the secretion of leptin via membrane associated estrogen receptor alpha in human placental cells.
References Gambino, Y.P., et al.: Molec. Cell. Res., 1823, 900 (2012); Somjen, D., et al.: J. Steroid. Biochem. Molec. Biol., 113, 171 (2009); Arreguin-Arevaloand, J.A.. et al.: Biol. Reproduct., 74, 202 (2006);

• Brand: TRC

Chemical properties

• Molecular weight: 359.42
• Formula: C₂₀H₂₅NO₅
• Color/Form: Neat
• InChI: InChI=1S/C20H25NO5/c1-20-7-6-13-12-3-2-11(22)8-15(12)17(21-26-10-19(24)25)9-14(13)16(20)4-5-18(20)23/h2-3,8,13-14,16,18,22-23H,4-7,9-10H2,1H3,(H,24,25)/b21-17-/t13-,14-,16+,18+,20+/m1/s1
• InChI key: InChIKey=AWARIMYXKAIIGO-HEHNFIMWSA-N
• SMILES: CC12CCC3c4ccc(O)cc4/C(=N/OCC(=O)O)CC3C1CCC2O