Etanidazole

CAS: 22668-01-5

Ref. TR-E889230

Product Information

• Name: Etanidazole
• Synonyms: N-(2-hydroxyethyl)-2-(2-nitroimidazol-1-yl)acetamide, 1H-Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, Brn 0919296, Etanidazol, Etanidazol [Spanish], Etanidazole (SR-2508), Etanidazole [USAN:INN], Etanidazolum, Etanidazolum [Latin], Ethanidazole, Imidazole-1-acetamide, N-(2-hydroxyethyl)-2-nitro-, N-(2-Hydroxyethyl)-1-(2-nitro-1-imidazolyl)acetamide, N-(2-Hydroxyethyl)-2-nitro-1H-imidazole-1-acetamide, N-(2-Hydroxyethyl)-2-nitroimidazole-1-acetamide, N-(2-hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide, NSC 301-467, Nsc 301467, Radinyl, Sr 2508, Unii-30Dka3Q1Hl

Description

Stability Hygroscopic
Applications Etanidazole is a kind of hypoxic radiosensitizer (a drug that sensitizes tumour cells to radiation therapy). Etanidazole is used in conjunction with Paclitaxel (P132500) to treat glioma, and is also used with Carboplatin (C177500) to treat advanced ovarian cancer.
References Brown, M.: Cancer Res., 59, 5863 (1999); Kumar, N., et al.: Biomaterials, 28, 886 (2007); Shulman, L., et al.: Int. J. Radiat. Oncol., 29, 545 (1994); Wang, F. & Wang, C.: J. Control. Release, 81, 263 (2002)

• Brand: TRC

Chemical properties

• Molecular weight: 214.18
• Formula: C₇H₁₀N₄O₄
• Color/Form: Neat
• InChI: InChI=1S/C7H10N4O4/c12-4-2-8-6(13)5-10-3-1-9-7(10)11(14)15/h1,3,12H,2,4-5H2,(H,8,13)
• SMILES: O=C(Cn1ccnc1[N+](=O)[O-])NCCO