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7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol
CAS: 315698-17-0
Ref. TR-E900485
| 1mg | 101.00 € | ||
| 5mg | 374.00 € | ||
| 10mg | 605.00 € |
Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol
Synonyms:
- ML311
CAS:
Description:
Applications 7-[(4-Ethyl-1-piperazinyl)[4-(trifluoromethyl)phenyl]methyl]-8-quinolinol is a selective inhibitor of the protein -protein interaction of Mcl-1 inhibitors and also a potential antitumor agents. Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
References Richard, D. J., et al.: Bioorg. Med. Chem., 21, 6642 (2013); Bruncko, M., et al.: J. Med. Chem., 58, 2180 (2015)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
415.45
Formula:
C23H24F3N3O
Color/Form:
Yellow Solid
InChI:
InChI=1S/C23H24F3N3O/c1-2-28-12-14-29(15-13-28)21(17-5-8-18(9-6-17)23(24,25)26)19-10-7-16-4-3-11-27-20(16)22(19)30/h3-11,21,30H,2,12-15H2,1H3
InChI key:
InChIKey=NGAPBLRRJSKIRT-UHFFFAOYSA-N
SMILES:
CCN1CCN(C(c2ccc(C(F)(F)F)cc2)c2ccc3cccnc3c2O)CC1
MDL:
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HS code:
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