Ethylenediamine P-Toluenesulfonate

CAS: 14034-59-4

Ref. TR-E917858

Product Information

• Name: Ethylenediamine P-Toluenesulfonate
• Synonyms: 1,2-Ethanediamine, 4-methylbenzenesulfonate (1:1), 1,2-Ethanediamine, mono(4-methylbenzenesulfonate) (9CI), Ethylenediamine, mono-p-toluenesulfonate (8CI), 2-Aminoethylammonium p-toluenesulfonate, Ethylenediamine monotosylate, NSC 14086, Xylometazoline Hydrochloride Impurity E, Xylometazoline Impurity E, 1,2-Ethanediamine, 4-methylbenzenesulfonate (1:1), 1,2-Ethanediamine, mono(4-methylbenzenesulfonate), 2-Aminoethanaminium 4-methylbenzenesulfonate, Ethylenediamine Mono-4-Toluene Sulfonate, Ethylenediamine p-toluenesulfonate, Ethylenediamine, mono-p-toluenesulfonate

Description

Impurity Xylometazoline EP Impurity E
Stability Hygroscopic
Applications Ethylenediamine P-Toluenesulfonate is a reactant used in the synthesis of antitumor agents. Also is an impurity of Xylometazoline (X749950), a vasoconstrictor involved in signal transduction, also used as a nasal decongestant. May be used in treatments involving ischemic injury due to the ability to shift energy metabolism from mitochondrial to glycolysis (2).
References 1. Fliri, A. et al.: J. Med. Chem. 2009 Dec 24;52(24):8038-46.2. Gohil, V. et al.: Nat Biotechnol. 2010 Mar;28(3):249-55.

• Brand: TRC

Chemical properties

• Molecular weight: 232.2999
• Formula: C₇H₈O₃S·C₂H₈N₂
• Color/Form: Neat
• InChI: 3-1-2-4/h2-5H,1H3,(H,8,9,10), 1-4H2, InChI=1S/C7H8O3S.C2H8N2/c1-6-2-4-7(5-3-6)11(8,9)10
• InChI key: InChIKey=HVCCFMAPGCBCHZ-UHFFFAOYSA-N
• SMILES: Cc1ccc(S(=O)(=O)O)cc1.NCCN