Ethyl 5-(2-Hydroxy-4,5-dimethoxybenzamido)thiophene-3-carboxylate

CAS: 185106-05-2

Ref. TR-E919168

Product Information

• Name: Ethyl 5-(2-Hydroxy-4,5-dimethoxybenzamido)thiophene-3-carboxylate
• CAS: 185106-05-2

Description

Applications Ethyl 5-(2-Hydroxy-4,5-dimethoxybenzamido)thiophene-3-carboxylate is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats (1,2). Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
References Masanao, K., et. al.: Eur. J. Pharmacol., 666, 218 (2011); Matsunaga, Y., et. al.: J. Pharmacol. Exp. Ther., 336, 791 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 352.36
• Formula: C₁₅H₁₆N₂O₆S
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C10H7F3O/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1-7H/b4-2+
• InChI key: InChIKey=JMKMLIWUWJNVIG-DUXPYHPUSA-N
• SMILES: O=C/C=C/c1cccc(C(F)(F)F)c1