(3R,4S,5S)-3-(1-Ethylpropoxy)-4,5-dihydroxy-1-cyclohexene-1-carboxylic Acid Ethyl Ester

CAS: 1201685-71-3

Ref. TR-E926105

Product Information

• Name: (3R,4S,5S)-3-(1-Ethylpropoxy)-4,5-dihydroxy-1-cyclohexene-1-carboxylic Acid Ethyl Ester
• Synonyms: ethyl (3R,4S,5S)-4,5-dihydroxy-3-pentan-3-yloxycyclohexene-1-carboxylate

Description

Applications (3R,4S,5S)-3-(1-Ethylpropoxy)-4,5-dihydroxy-1-cyclohexene-1-carboxylic Acid Ethyl Ester is the impurity of the anti-viral drug Oseltamivir Phosphate (O701000), which is an orally active inhibitor of influenza virus neuraminidase.
References Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998); Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998); Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999); Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000); Osato, H., et al.: Org. Lett., 12, 60 (2010);

• Brand: TRC

Chemical properties

• Molecular weight: 272.337
• Formula: C₁₄H₂₄O₅
• Color/Form: Neat
• InChI: InChI=1S/C14H24O5/c1-4-10(5-2)19-12-8-9(14(17)18-6-3)7-11(15)13(12)16/h8,10-13,15-16H,4-7H2,1-3H3/t11-,12+,13-/m0/s1
• InChI key: InChIKey=YONORCNNWKSULH-XQQFMLRXSA-N
• SMILES: CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@@H](O)[C@@H](O)C1