Ethyl 2-​(2,​4,​5-​Trimethoxybenzamido)​thiazole-​4-​carboxylate

CAS: 185105-98-0

Ref. TR-E927143

Product Information

• Name: Ethyl 2-​(2,​4,​5-​Trimethoxybenzamido)​thiazole-​4-​carboxylate
• Synonyms: ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate

Description

Applications Ethyl 2-​(2,​4,​5-​Trimethoxybenzamido)​thiazole-​4-​carboxylate is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats (1,2). Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
References Masanao, K., et. al.: Eur. J. Pharmacol., 666, 218 (2011); Matsunaga, Y., et. al.: J. Pharmacol. Exp. Ther., 336, 791 (2011)

• Brand: TRC

Chemical properties

• Molecular weight: 366.39
• Formula: C₁₆H₁₈N₂O₆S
• Color/Form: Neat
• InChI: InChI=1S/C16H18N2O6S/c1-5-24-15(20)10-8-25-16(17-10)18-14(19)9-6-12(22-3)13(23-4)7-11(9)21-2/h6-8H,5H2,1-4H3,(H,17,18,19)
• InChI key: InChIKey=SJHCUXCOGGKFAI-UHFFFAOYSA-N
• SMILES: CC(C)OP(OC(C)C)OC(C)C