Everolimus Isomer C (>60%, contains everolimus)
CAS: 908340-97-6
Ref. TR-E945425
| 1mg | 273.00 € | ||
| 10mg | 1,346.00 € | ||
| 25mg | 2,401.00 € |
Estimated delivery in United States, on Monday 4 Nov 2024
Product Information
Name:
Everolimus Isomer C (>60%, contains everolimus)
Controlled Product
Synonyms:
- Rapamycin
- 9,14-deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxo- (9CI)
- Everolimus Isomer C
- 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-42-O-(2-hydroxyethyl)-14-oxorapamycin
- Everolimus oxepane isomer
- (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,28R,34aS)-9,10,12,13,14,21,22,23,24,25,26,28,32,33,34,34a-Hexadecahydro-9,28-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,28-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,27,29(4H,6H,31H)-pentone
Description:
Stability Unstable in solution, revert back to Everolimus
Applications Everolimus Isomer C is an isomer of Everolimus (E945400), a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.
References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
958.22
Formula:
C53H83NO14
Color/Form:
Neat
InChI:
InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-34(3)50(59)53(62,68-40)52(61)54-23-15-14-18-41(54)51(60)67-45(36(5)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)35(4)27-38(7)48(58)49(65-10)47(57)37(6)26-32/h11-13,16-17,27,32,34-37,39-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,38-27+/t32-,34-,35?,36-,37-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1
InChI key:
InChIKey=USDOYNAPNXMXOE-MQKHQQMESA-N
SMILES:
CO[C@H]1C[C@@H]2CC[C@@H](C)C(=O)C(O)(O2)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@@H](OCCO)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C/1C
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