Product Information
Name:
Fidaxomicin Dimethoxy Impurity
Synonyms:
- (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dimethoxybenzoyl)-2-O-methyl-beta-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-beta-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one
- 3''',5'''-Di-O-methyltiacumicin B
Description:
Applications 3’’’,5’’’-Dideshydroxy-3’’’,5’’’-dimethoxy Fidaxomicin is a derivative of Fidaxomicin (F335400), a nonabsorbed macrocyclic antibiotic, and is also the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years.
References Babakhani, F., et al.: Clin. Infect. Dis., 55, S162 (2012); Venugopal, A., et al.: Clin. Infect. Dis., 54, 568 (2012)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
1086.09
Formula:
C54H78Cl2O18
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C54H78Cl2O18/c1-15-32-24-28(6)35(58)20-18-17-19-33(25-68-53-47(67-14)42(61)44(31(9)69-53)71-51(64)37-34(16-2)38(55)46(66-13)39(56)45(37)65-12)50(63)70-36(30(8)57)22-21-27(5)23-29(7)43(32)72-52-41(60)40(59)48(54(10,11)74-52)73-49(62)26(3)4/h17-19,21,23-24,26,30-32,35-36,40-44,47-48,52-53,57-61H,15-16,20,22,25H2,1-14H3/b18-17-,27-21+,28-24+,29-23-,33-19+/t30-,31-,32+,35-,36+,40-,41+,42+,43+,44-,47+,48+,52?,53-/m1/s1
InChI key:
InChIKey=VSQXOITUBILBJL-RTZOBUOVSA-N
SMILES:
CCc1c(Cl)c(OC)c(Cl)c(OC)c1C(=O)O[C@H]1[C@H](O)[C@H](OC)[C@H](OC/C2=C/C=C\C[C@@H](O)/C(C)=C\[C@H](CC)[C@@H](OC3OC(C)(C)[C@@H](OC(=O)C(C)C)[C@H](O)[C@@H]3O)/C(C)=C\C(C)=C/C[C@@H]([C@@H](C)O)OC2=O)O[C@@H]1C
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