Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
FK866
Controlled Product
Synonyms:
- (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide
- APO 866
- K 22.175
- 2-Propenamide, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-, (2E)-
- Apo 866
- Apo866
- Fk 866
- Fk866
CAS:
Description:
Applications FK866 is a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), that induces tumor cell apoptosis, and thus is a potential anticancer drug.
References Hasmann, M., Schemainda, I.: Cancer Res., 63, 7436 (2003); Khan, J., et a.: Nat. Struct. Mol. Biol., 13, 582 (2006);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
391.51
Formula:
C24H29N3O2
Color/Form:
Off-White to Light Yellow Solid
InChI:
InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+
InChI key:
InChIKey=KPBNHDGDUADAGP-VAWYXSNFSA-N
SMILES:
O=C(/C=C/c1cccnc1)NCCCCC1CCN(C(=O)c2ccccc2)CC1
MDL:
Melting point:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-F370030 FK866
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