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4-Fluoro-Alpha-(2-methyl-1-oxopropyl)-Gamma-oxo-N,Beta-diphenyl-benzenebutanamide
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4-Fluoro-Alpha-(2-methyl-1-oxopropyl)-Gamma-oxo-N,Beta-diphenyl-benzenebutanamide

CAS: 125971-96-2

Ref. TR-F593700

1g
240.00 €
Estimated delivery in United States, on Tuesday 21 May 2024

Product Information

Name:
4-Fluoro-Alpha-(2-methyl-1-oxopropyl)-Gamma-oxo-N,Beta-diphenyl-benzenebutanamide
Controlled Product
Synonyms:
  • 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxopentanoic acid phenylamide
  • 4-Fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-N,beta-diphenylbenzenebutanamide
  • (4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butane amide(M-4)
  • 2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
  • 4-Fluoro-Alpha-(2-Methyl-1-Oxopropyl)-Gamma-Oxo-N,Beta-Diphenylbenzene Butaneamide
  • 4-Fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-N,bata-diphenylbenzene butaneamide (M4)
  • 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenylbenzenebutanamide
  • 4-Fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butanamide
  • 4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butane amide
  • 4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butane amideIsobutyrylacetic acid methyl ester
  • See more synonyms
  • 4-fluoro-α-[2-methyl-1-oxopropyl]-γ-oxo-N,β-diphenylbenzene butaneamide
  • Benzenebutanamide, 4-fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-
  • Fr Dvyr&Yvmr&Vy1&1
  • M-4
  • M-4(atovastatin's intermediate)
  • benzenebutanamide, 4-fluoro-alpha-(2-methyl-1-oxopropyl)-gamma-oxo-N,beta-diphenyl-
Description:

Impurity Atorvastatin Diketo Amide Impurity
Applications An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Winters, R., et al.: J. Med. Chem., 36, 1735 (1993), Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (2000), Istvan, E., et al.: Science, 292, 1160 (2001)

Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
417.47
Formula:
C26H24FNO3
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C26H24FNO3/c1-17(2)24(29)23(26(31)28-21-11-7-4-8-12-21)22(18-9-5-3-6-10-18)25(30)19-13-15-20(27)16-14-19/h3-17,22-23H,1-2H3,(H,28,31)
InChI key:
InChIKey=SNPBHOICIJUUFB-UHFFFAOYSA-N
SMILES:
CC(C)C(=O)C(C(=O)Nc1ccccc1)C(C(=O)c1ccc(F)cc1)c1ccccc1
MDL:
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Hazard Info

UN Number:
EQ:
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H Statements:
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Forbidden to fly:
Hazard Info:
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LQ:

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