3-Fluorophenyl Bicalutamide

CAS: 1166228-30-3

Ref. TR-F595335

Product Information

• Name: 3-Fluorophenyl Bicalutamide
• Synonyms: (RS)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(3-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide, Bicalutamide Related Compound B (USP), Bicalutamide Related Compound B

Description

Impurity Bicalutamide USP Related Compound B/ Bicalutamide EP Impurity B
Applications 3-Fluorophenyl Bicalutamide (Bicalutamide USP Related Compound B) is a steroisomer of Bicalutamide (B382000), non-steroidal peripherally active anti-androgen. Used as an antiandrogen, antineoplastic (hormonal).
References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),

• Brand: TRC

Chemical properties

• Molecular weight: 430.37
• Formula: C₁₈H₁₄F₄N₂O₄S
• Color/Form: Neat
• InChI: InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-4-2-3-12(19)7-14)16(25)24-13-6-5-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)
• SMILES: CC(O)(CS(=O)(=O)c1cccc(F)c1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1