(E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7

CAS: 93957-50-7

Ref. TR-F595672

Product Information

• Name: (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7
• Synonyms: (E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal-d7, (2E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal-d7, (2E)-3-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-Indol-2-Yl]-2-Propenal, (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde, (E)-3-[3'-(4''-Fluorophenyl)-1'-(1''-Methylethyl)-1H-Indol-2''-Yl]-2-Propnal, (E)-3-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-2-propenal, (E)-3-[3-(4-fluorophenyl)-1-(1-methylethyl)-2-indolyl]propenal, 2-Propenal, 3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (2E)-, 2-Propenal,3-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-, (E)-, Fluvastatin intermediate
• CAS: 93957-50-7

Description

Applications (E)-3-(3-(4-Fluorophenyl)-1-isopropyl-1H-indol-2-yl)acrylaldehyde-d7 an isotope labelled reactant used in the synthesis of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor.
References Sacharia, J.R., et. al.: J. Org. Chem., 75, 7514 (2010); Kim, A., Kim, I.S.: Bull. Korean Chem. Soc., 32, 3748 (2011); Yuan, J., et al.: Atherosclerosis, 87, 147 (1991); Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992); Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 314.405
• Formula: C₂₀D₇H₁₁FNO
• Color/Form: Neat
• InChI: InChI=1S/C20H18FNO/c1-14(2)22-18-7-4-3-6-17(18)20(19(22)8-5-13-23)15-9-11-16(21)12-10-15/h3-14H,1-2H3/b8-5+/i1D3,2D3,14D
• InChI key: InChIKey=DVWHSTKQJBIYCK-VETRHNNLSA-N
• SMILES: [2H]C([2H])([2H])C([2H])(n1c(/C=C/C=O)c(-c2ccc(F)cc2)c2ccccc21)C([2H])([2H])[2H]