N-Fmoc-5-fluoro-L-tryptophan

CAS: 908846-88-8

Ref. TR-F622905

Product Information

• Name: N-Fmoc-5-fluoro-L-tryptophan
• Synonyms: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(5-fluoro-1H-indol-3-yl)propanoic acid

Description

Applications N-Fmoc-5-fluoro-L-tryptophan is a protected form of 5-fluoro-L-tryptophan, a compound that selectively binds to human serum albumin (HSA), the most abundant protein in the circulatory system. 5-Fluoro-L-tryptophan is also a derivative of L-Tryptophan is an amino acid that is a metabolic precursor of Norepinephrine (N674500) and Serotonin (S274980).
References Bunney, W., et al.: Am. J. Psych., 127, 872 (1971); Chanut, E., et al.: Biochem. Pharma., 44, 2082 (1992); Gerig, J. & Klinkenborg, J.: J. Am. Chem. Soc., 102, 4267 (1980)

• Brand: TRC

Chemical properties

• Molecular weight: 444.454
• Formula: C₂₆H₂₁FN₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C26H21FN2O4/c27-16-9-10-23-21(12-16)15(13-28-23)11-24(25(30)31)29-26(32)33-14-22-19-7-3-1-5-17(19)18-6-2-4-8-20(18)22/h1-10,12-13,22,24,28H,11,14H2,(H,29,32)(H,30,31)/t24-/m0/s1
• InChI key: InChIKey=GIFXTRKMFUWKHR-DEOSSOPVSA-N
• SMILES: O=C(N[C@@H](Cc1c[nH]c2ccc(F)cc12)C(=O)O)OCC1c2ccccc2-c2ccccc21