Folinic Acid Calcium Salt

CAS: 1492-18-8

Ref. TR-F680320

Product Information

• Name: Folinic Acid Calcium Salt
• Synonyms: Calcium folinate, Calcium (2S)-2-[[4-[[[(6RS)-2-amino-5-formyl-4-oxo1,4,5,6,7,8-hexahydropteridin-6-yl]methyl]amino]benzoyl]amino]pentanedioate, Calcium 5-formyltetrahydrofolate, Calcium L-folinate, Calcium folinate, Calcium leucovorin, Folidan, Lederfoline, Leucovorin calcium, Leucovorin calcium salt, NSC 3590, Rescuvolin, Wellcovorin, Folic Acid Related Compound A as Calcium Salt, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), Calcium <span class="text-smallcaps">L</span>-folinate, Calcium Folinate, Calcium Folinate(Folinic Acid)(Rg), Calcium L-Folinate, Calcium2-[4-[(2-Amino-5-Formyl-4-Oxo-1,6,7,8-Tetrahydropteridin-6-Yl)Methylamino]Benzoyl] Aminopentanedioate, Calciumfolinat, Folinate De Calcium, Folinate-SF calcium, Folinato Calcico, Folinic acid Calcium salt, Folinic acid calcium salt USP28, Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), <span class="text-smallcaps">L</span>-, Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), L-, L-Calcium Folinate, L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), Leucovorin Calcium, LeucovorinCalcium, Leucovorine calcium, Nsc 3590, calcium (2S)-2-({[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}amino)pentanedioate, calcium (2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl)amino]pentanedioate

Description

Stability Hygroscopic
Applications Folinic Acid Calcium Salt is a derivative of Folic Acid (F680300), a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. Has been shown to be partially effective in the treatment children suffering from autism spectrum disorders (ASDs).
References Frye, R. et al.: Mol. Psych., 18, 369 (2013); Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 511.50
• Formula: C₂₀H₂₁N₇O₇·Ca
• Color/Form: Light Yellow
• InChI: InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1
• SMILES: Nc1nc(=O)c2c([nH]1)NCC(CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1)N2C=O.[Ca+2]