Folitixorin (~80%) (Mixture of Diastereomers)

CAS: 3432-99-3

Ref. TR-F680350

Product Information

• Name: Folitixorin (~80%) (Mixture of Diastereomers)
• Synonyms: L-Glutamic acid, N-[4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-, Glutamic acid, N-[p-(3-amino-5,6,6a,7-tetrahydro-1-hydroxyimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-, L- (8CI), Imidazo[1,5-f]pteridine, L-glutamic acid deriv., N-[4-(3-Amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-L-glutamic acid, (+)-5,10-Methylene-5,6,7,8-tetrahydrofolic acid, 5,10-Methylene-(6RS)-tetrahydrofolic acid, 5,10-Methylene-5,6,7,8-tetrahydrofolic acid, 5,10-Methylenetetrafolate, 5,10-Methylenetetrahydrofolic acid, Folic acid, tetrahydro-N5,N10-methylene-, Folitixorin, N5,N10-Methylene-5,6,7,8-tetrahydrofolic acid, N5,N10-Methylenetetrahydrofolic acid, N5,N10-Methylenetetrahydropteroylglutamic acid, (2S)-2-[4-[(6aRS)-3-Amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzamido]pentanedioic acid, (6aRS)-5,10-Methylenetetrahydrofolic acid, (2s)-2-(4-(3-Amino-1-oxo-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzamido)pentanedioic acid, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-(3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-, Anx-510, Folic acid, tetrahydro-N⁵,N¹⁰-methylene-, Glutamic acid, N-[p-(3-amino-5,6,6a,7-tetrahydro-1-hydroxyimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-, <span class="text-smallcaps">L</span>-, Imidazo[1,5-f]pteridine, <span class="text-smallcaps">L</span>-glutamic acid deriv., L-glutamic acid, N-[4-(3-amino-5,6,6a,7-tetrahydro-1-hydroxyimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-, N-[4-(3-Amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, N-[4-(3-amino-1-hydroxy-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-L-glutamic acid, N-{4-[(6aR)-3-amino-1-oxo-1,4,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid, N⁵,N¹⁰-Methylene-5,6,7,8-tetrahydrofolic acid, N⁵,N¹⁰-Methylenetetrahydrofolic acid, N⁵,N¹⁰-Methylenetetrahydropteroylglutamic acid

Description

Stability Hygroscopic, Moisture Sensitive, Temperature Sensitive
Applications A stable folate lyophilized compound suitable for use in the treatment of cancer and other therapies.
References Park, H., et al.: Science, 268, 1866 (1995), Banerjee, R., et al.: J. Biol. Chem., 282, 14916 (2007), Klar, T., et al.: J. Mol. Biol., 366, 954 (2007),

• Brand: TRC

Chemical properties

• Molecular weight: 457.44
• Formula: C₂₀H₂₃N₇O₆
• Color/Form: Neat
• InChI: InChI=1S/C20H23N7O6/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31)/t12?,13-/m0/s1
• InChI key: InChIKey=QYNUQALWYRSVHF-ABLWVSNPSA-N
• SMILES: Nc1nc2c(c(=O)[nH]1)N1CN(c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)CC1CN2