Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
GDC-0879 Hydrochloride
Controlled Product
Synonyms:
- 2,3-Dihydro-5-[1-(2-hydroxyethyl)-3-(4-pyridinyl)-1H-pyrazol-4-yl]-1H-Inden-1-one Oxime Hydrochloride
- Gdc-0879
CAS:
Description:
Stability Hygroscopic
Applications GDC-0879 is a RAF inhibitor used in the treatment of melanoma tumors associated with the BRAF serine/threonine kinase.
References Hoeflich, K. et al.: Canc. Res., 69, 3042 (2009); Hansen, J. ET AL.: Bioorg. Med. Chem. Lett., 18, 4692 (2008);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
370.83
Formula:
C19H19ClN4O2
Color/Form:
Neat
InChI:
InChI=1S/C19H18N4O2.ClH/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25;/h1,3,5-8,11-12,24-25H,2,4,9-10H2;1H/b22-18-;
InChI key:
InChIKey=WCGFRHQEGOIVHC-QNCGTCMPSA-N
SMILES:
Cl.OCCn1cc(-c2ccc3c(c2)CC/C3=N/O)c(-c2ccncc2)n1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-G299980 GDC-0879 Hydrochloride
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