Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
GDC-0980
Synonyms:
- Apitolisib
- G 038390
- G 038390.1
- GDC 0980.1
- GNE 390
- RG 7422
- Gdc-0980
- Gne 390
- (S)-1-(4-((2-(2-aMinopyriMidin-5-yl)-7-Methyl-4-Morpholinothieno[3,2-d]pyriMidin-6-yl)Methyl)piperazin-1-yl)-2-hydroxypropan-1-one
- Gdc-0980 (Rg7422)
- See more synonyms
- (2S)-1-(4-{[2-(2-Amino-5-pyrimidinyl)-7-methyl-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl}-1-piperazinyl)-2-hydroxy-1-propanone
CAS:
Description:
Applications GDC-0980 is used in the synthesis of PI3K inhibitors to treat carcinomas. Potent PI3K/mTOR dual Inhibitor.
References Sampath, D. et al.: Neoplasoa, 15, 694 (2013); Serova, M. et al.: Canc. Chemother. Pharm., 71, 1297 (2013);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
498.6
Formula:
C23H30N8O3S
Color/Form:
White to Light Yellow Solid
InChI:
InChI=1S/C23H30N8O3S/c1-14-17(13-29-3-5-31(6-4-29)22(33)15(2)32)35-19-18(14)27-20(16-11-25-23(24)26-12-16)28-21(19)30-7-9-34-10-8-30/h11-12,15,32H,3-10,13H2,1-2H3,(H2,24,25,26)/t15-/m0/s1
InChI key:
InChIKey=YOVVNQKCSKSHKT-HNNXBMFYSA-N
SMILES:
Cc1c(CN2CCN(C(=O)[C@H](C)O)CC2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12
MDL:
Melting point:
Boiling point:
Flash point:
Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-G303000 GDC-0980
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