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GS-563117
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GS-563117

Ref. TR-G563115

100mg
1,589.00 €
Estimated delivery in United States, on Friday 29 Nov 2024

Product Information

Name:
GS-563117
Controlled Product
Synonyms:
  • (S)-5-Fluoro-2-(1-((8-oxo-8,9-dihydro-7H-purin-6-yl)amino)propyl)-3-phenylquinazolin-4(3H)-one
Description:

Applications GS-563117 is Idelalisib's (C124800) metabolite. Idelalisib is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.
References Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
431.422
Formula:
C22H18FN7O2
Color/Form:
Neat
InChI:
InChI=1S/C22H18FN7O2/c1-2-14(26-18-17-19(25-11-24-18)29-22(32)28-17)20-27-15-10-6-9-13(23)16(15)21(31)30(20)12-7-4-3-5-8-12/h3-11,14H,2H2,1H3,(H3,24,25,26,28,29,32)/t14-/m0/s1
InChI key:
InChIKey=PEYAOBRJGKFVDV-AWEZNQCLSA-N
SMILES:
CC[C@H](Nc1ncnc2[nH]c(=O)[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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