1-Glycidylpiperidine
CAS: 4945-53-3
Ref. TR-G582385
| 100mg | Discontinued | ||
| 250mg | Discontinued | ||
| 500mg | Discontinued |
Product Information
Name:
1-Glycidylpiperidine
Synonyms:
- 1-(2,3-Epoxypropyl)-piperidine
- 1-(Oxiranylmethyl)-piperidine
- 1-(2-Oxiranylmethyl)piperidine
- 1,2-Epoxy-3-(1-piperidinyl)propane
- 1-(Oxiranylmethyl)piperidine
- 1-[(Oxiran-2-yl)methyl]piperidine
- 3-Piperidinopropylene Oxide
- N-(2,3-Epoxypropyl)piperidine
Description:
Applications 1-Glycidylpiperidine is an intermediate in the synthesis of BGP 15 (B411990). BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.
References Sarszegi, Z., et al.: Mol. Cell. Biol., 365, 129-137 (2012); Ohlen, S. B., et al.: Proc. Natl. Acad. Sci. U.S.A., 114, 5035-5040 (2017)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
141.21
Formula:
C8H15NO
Color/Form:
Colourless oil
InChI:
InChI=1S/C8H15NO/c1-2-4-9(5-3-1)6-8-7-10-8/h8H,1-7H2
InChI key:
InChIKey=JWYRPOYJRRHHIL-UHFFFAOYSA-N
SMILES:
C1CCN(CC2CO2)CC1
MDL:
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