Estimated delivery in United States, on Monday 1 Jul 2024
Product Information
Name:
GNF 5837
Synonyms:
- N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]-urea
CAS:
Description:
Applications GNF 5837 is a potent pan-Trk inhibitor which has selectivity for tropomyosin-receptor-kinase (Trk).
References Albaugh, et al.: Med. Chem. Lett. 3, 140 (2012); Deng, X., et al.: J. Med. Chem., 53, 6934 (2010)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
535.492
Formula:
C28H21F4N5O2
Color/Form:
Dark Orange Solid
InChI:
InChI=1S/C28H21F4N5O2/c1-15-4-6-19(35-27(39)37-25-11-16(28(30,31)32)5-9-22(25)29)13-23(15)34-18-7-8-20-21(12-17-3-2-10-33-17)26(38)36-24(20)14-18/h2-14,33-34H,1H3,(H,36,38)(H2,35,37,39)/b21-12+
InChI key:
InChIKey=BSLZIUNPWSDRII-UHFFFAOYSA-N
SMILES:
CC1CNC(C)C(c2ccccc2)O1.Cl
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-G766305 GNF 5837
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