Product Information
Name:
GSK 1059615 Sodium Salt Hydrate
Synonyms:
- (5Z)-5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidinedione Sodium Salt Hydrate
Description:
Applications GSK 1059615 is a potent inhibitor of PI 3-kinase α (PI3Kα). GSK 1059615 inhibits proliferation in BT474 cells and attenuates MAPK signaling.
References Saadia, et al.: Clin. Cancer Res., 15, 3029 (2009), Knight, et al.: ACS Med. Chem. Lett., 1, 39 (2010),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
355.35 + x(18.02)
Formula:
C18H11N3NaO2S•xH2O
Color/Form:
Pale Yellow Solid
InChI:
InChI=1S/C18H11N3O2S.Na.H2O/c22-17-16(24-18(23)21-17)10-11-1-2-15-14(9-11)13(5-8-20-15)12-3-6-19-7-4-12;;/h1-10H,(H,21,22,23);;1H2/q;+1;/p-1/b16-10-;;
InChI key:
InChIKey=KKSRFFGUIONCPS-FLPKAINGSA-M
SMILES:
O.O=C1S/C(=C\c2ccc3nccc(-c4ccncc4)c3c2)C(=O)N1[Na]
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