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N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
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N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide

CAS: 1140-81-4

Ref. TR-H114085

1g
722.00 €
5g
2,748.00 €
500mg
381.00 €
Estimated delivery in United States, on Monday 16 Dec 2024

Product Information

Name:
N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide
Controlled Product
Synonyms:
  • N-Acetyl-4-hydroxy-2-methyl-6-quinolinamine
  • N-(2-methyl-4-oxo-1,4-dihydroquinolin-6-yl)acetamide
Description:

Applications N-(4-Hydroxy-2-methyl-6-quinolinyl)acetamide is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
References Gao, Y., et. al.: Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al.: Methods Enzymol, 406, 554 (2006)

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
216.24
Formula:
C12H12N2O2
Color/Form:
Neat
InChI:
InChI=1S/C12H12N2O2/c1-7-5-12(16)10-6-9(14-8(2)15)3-4-11(10)13-7/h3-6H,1-2H3,(H,13,16)(H,14,15)
InChI key:
InChIKey=INGXYDNOMOPBLY-UHFFFAOYSA-N
SMILES:
CC(=O)Nc1ccc2nc(C)cc(O)c2c1
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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