Product Information
Name:
2-(2-Heptynylthio)phenol Acetate
Synonyms:
- APHS
- Phenol, 2-(2-Heptyn-1-Ylthio)-, Acetate
- Phenol, 2-(2-heptynylthio)-, acetate
Description:
Applications An O-acetyl, S-alkyl thio ether of 2-thio phenol. It is a potent inhibitor of both COX-1 and COX-2, with IC50 values of 17 and 0.8uM for human recombinant COX-1 and COX-2 respectively. APHS exhibits 20-fold selectivity toward the inhibition of COX-2, yet it is still more potent than aspirin in the inhibition of COX-1.
References Kalgutkar, A.S., et a.: Science, 280, 1268 (1998)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
262.37
Formula:
C15H18O2S
Color/Form:
Clear Colorless to Light Yellow Oil
SMILES:
CCCCC#CCSc1ccccc1OC(C)=O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
