Hernandezine

CAS: 6681-13-6

Ref. TR-H288945

Product Information

• Name: Hernandezine
• Synonyms: (1S,14S)-9,19,20,21,25-pentamethoxy-15,30-dimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-3(36),4,6(35),8(34),9,11,18(33),19,21,24,26,31-dodecaene, (+)-Hernandezine, (4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,20,21,22,26-pentamethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,20,21,22,26-pentamethoxy-4,17-dimethyl-, (4aS,16aS)-, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, berbaman deriv., Berbaman, 5,6,6',7,12-pentamethoxy-2,2'-dimethyl-, (1beta)-, Berbaman, 5,6,6′,7,12-pentamethoxy-2,2′-dimethyl-, (1β)-, Hernandesine, Thalicsimine
• CAS: 6681-13-6

Description

Applications Hernandezine is a novel anticancer AMPK activator identified as a major major active constituent of Thalictrum Ranunculaceae.
References Song, Y. et al.: J. Pharm. Biomed. Anal., 141, 132 (2017);

• Brand: TRC

Chemical properties

• Molecular weight: 652.776
• Formula: C₃₉H₄₄N₂O₇
• Color/Form: Neat
• InChI: InChI=1S/C39H44N2O7/c1-40-16-14-25-21-32(43-4)34-22-28(25)29(40)18-23-8-11-26(12-9-23)47-33-20-24(10-13-31(33)42-3)19-30-35-27(15-17-41(30)2)36(44-5)38(45-6)39(46-7)37(35)48-34/h8-13,20-22,29-30H,14-19H2,1-7H3/t29-,30-/m0/s1
• InChI key: InChIKey=FUZMQNZACIFDBL-KYJUHHDHSA-N
• SMILES: COc1ccc2cc1Oc1ccc(cc1)C[C@H]1c3cc(c(OC)cc3CCN1C)Oc1c(OC)c(OC)c(OC)c3c1[C@H](C2)N(C)CC3