rac Homatropine Hydrobromide

CAS: 51-56-9

Ref. TR-H459200

Product Information

• Name: rac Homatropine Hydrobromide
• Synonyms: Homatropine hydrobromide, (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2RS)-2-hydroxy-2-phenylacetate hydrobromide, Homatropine bromide, Isopto Homatropine, Mandelic acid tropine ester hydrobromide, 1alphaH,5alphaH-Tropan-3alpha-ol, mandelate (ester), hydrobromide (8CI), Benzeneacetic acid, alpha-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (9CI), Benzeneacetic acid, alpha-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-, (+/-)-Homatropine bromide, Benzeneacetic acid, alpha-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1), (1R,5S)-3-{[(2R)-2-hydroxy-2-phenylacetyl]oxy}-8-methyl-8-azoniabicyclo[3.2.1]octane, (±)-Homatropine bromide, 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, mandelate (ester), hydrobromide, 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate, 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate Hydrobromide (1:1), Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1), Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-, Homatropine HBr, Homatropine Hydrobromide, alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide

Description

Applications Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.
References Mattila, M.J. et al.: Ann. Med. Exp. Biol. Fen., 45, 412 (1967); Gambill, H. et al.: Arch. Ophthamol., 77, 740 (1967); Sund, R.B.: Med. Norsk Farmac. Sels., 33, 143 (1971);

• Brand: TRC

Chemical properties

• Molecular weight: 356.25
• Formula: C₁₆H₂₁NO₃·BrH
• Color/Form: White To Off-White
• InChI: InChI=1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H/t12-,13+,14+,15-;/m1./s1
• InChI key: InChIKey=PLNIOACITGBKQB-UHFFFAOYSA-N
• SMILES: Br.CN1[C@H]2CC[C@@H]1C[C@H](OC(=O)C(O)c1ccccc1)C2