Honokiol

CAS: 35354-74-6

Ref. TR-H669560

Product Information

• Name: Honokiol
• Synonyms: 3',5-Di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol, [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl- (9CI), 3',5-Diallyl-2,4'-biphenyldiol, NSC 293100, 2-Allyl-4-(5-allyl-2-hydroxyphenyl)phenol, 2-[4-Hydroxy-3-(2-propenyl)phenyl]-4-(2-propenyl)phenol, 3',5-Di(Prop-2-En-1-Yl)Biphenyl-2,4'-Diol, 3,5'-Diallyl-4,2'-dihydroxybiphenyl, 3′,5-Di-2-propen-1-yl[1,1′-biphenyl]-2,4′-diol, 3′,5-Diallyl-2,4′-biphenyldiol, Nsc 293100, [1,1′-Biphenyl]-2,4′-diol, 3′,5-di-2-propen-1-yl-, [1,1′-Biphenyl]-2,4′-diol, 3′,5-di-2-propenyl-
• CAS: 35354-74-6

Description

Applications Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. Recent studies show that Honokiol displays antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, without appreciable toxicity. Honokiol has been shown to inhibit the bone metastatic growth of human prostate cancer cells.
References Fried, L.E. et al.: Antioxid. Redox Signal,. 11, 1139 (2009); Chen, X.R. et al.: Int. J. Oral Sci., 3, 34 (2011); Shigemura, K. et al.: Cancer, 109, 1279 (2007); Bai, X. et al.: J. Biol. Chem., 278, 35501 (2003);

• Brand: TRC

Chemical properties

• Molecular weight: 266.33
• Formula: C₁₈H₁₈O₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
• InChI key: InChIKey=FVYXIJYOAGAUQK-UHFFFAOYSA-N
• SMILES: C=CCc1ccc(O)c(-c2ccc(O)c(CC=C)c2)c1