Hydrolyzed Pomalidomide M10

CAS: 918314-45-1

Ref. TR-H714900

Product Information

• Name: Hydrolyzed Pomalidomide M10
• Synonyms: 4-Amino-?-(aminocarbonyl)-1,3-dihydro-1,3-dioxo-2H-isoindole-2-butanoic Acid
• CAS: 918314-45-1

Description

Applications Hydrolyzed Pomalidomide M10 is an impurity of pomalidomide (P688200), which is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)

• Brand: TRC

Chemical properties

• Molecular weight: 291.26
• Formula: C₁₃H₁₃N₃O₅
• Color/Form: Off-White to Yellow Solid
• InChI: InChI=1S/C13H13N3O5/c14-7-3-1-2-6-10(7)13(21)16(12(6)20)8(11(15)19)4-5-9(17)18/h1-3,8H,4-5,14H2,(H2,15,19)(H,17,18)