Hydrocortisone 3-(O-Carboxymethyl)oxime

CAS: 43188-86-9

Ref. TR-H716568

Product Information

• Name: Hydrocortisone 3-(O-Carboxymethyl)oxime
• Synonyms: 2-[[[(11beta)-11,17,21-Trihydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy]acetic Acid, Cortisol 3-(O-Carboxymethyl)oxime, Cortisol 3-(Carboxymethyloxime), [[[(11beta)-11,17,21-Trihydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy]acetic Acid

Description

Applications Hydrocortisone 3-(O-Carboxymethyl)oxime is a model steroid that was coupled with bovine serum albumin (F-3-O-CMO-BSA) and used as immunogen to raise the antiserum in New Zealand white rabbits.It is derived from Hydrocortisone (H714615), which is a topical corticosteroid (1), more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland (2). Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis (3); suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Nara, S., et al.: Anal. Biochem., 373, 18-25 (2008)

• Brand: TRC

Chemical properties

• Molecular weight: 435.511
• Formula: C₂₃H₃₃NO₇
• Color/Form: Off-White
• InChI: InChI=1S/C23H33NO7/c1-21-7-5-14(24-31-12-19(28)29)9-13(21)3-4-15-16-6-8-23(30,18(27)11-25)22(16,2)10-17(26)20(15)21/h9,15-17,20,25-26,30H,3-8,10-12H2,1-2H3,(H,28,29)/b24-14+/t15-,16-,17-,20+,21-,22-,23-/m0/s1
• InChI key: InChIKey=WXAWNCDYPXVODT-ZAKIEOBNSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=C/C(=N/OCC(=O)O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO