4-Hydroxyantipyrine

CAS: 1672-63-5

Ref. TR-H801805

Product Information

• Name: 4-Hydroxyantipyrine
• Synonyms: Antipyrine, 4-hydroxy- (6CI,7CI,8CI), 1,2-Dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one, 4-Hydroxy-1,5-dimethyl-3-oxo-2-phenyl pyrazoline, 4-Hydroxyphenazone, NSC 174055, Nsc 174055, 3H-Pyrazol-3-one, 1,2-dihydro-4-hydroxy-1,5-dimethyl-2-phenyl- (9CI), 4-hydroxy-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one

Description

Applications 4-Hydroxyantipyrine is a metabolite of antipyrine (A697500) which is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
References Ohkawa Y et al. Biol Pharm Bull. 2001 Dec;24(12):1404-10.Jorquera F et al. Dig Dis Sci. 2001 Feb;46(2):352-9.Farrell GC et al. Br J Clin Pharmacol. 1984 Oct;18(4):559-65.Yoshimura H et al. Biochem Pharmacol. 1968 Aug;17(8):1511-6.

• Brand: TRC

Chemical properties

• Molecular weight: 204.22
• Formula: C₁₁H₁₂N₂O₂
• Color/Form: Off-White
• InChI: InChI=1S/C11H12N2O2/c1-8-10(14)11(15)13(12(8)2)9-6-4-3-5-7-9/h3-7,14H,1-2H3
• InChI key: InChIKey=SKVPTPMWXJSBTF-UHFFFAOYSA-N
• SMILES: Cc1c(O)c(=O)n(-c2ccccc2)n1C