3-Hydroxymethylantipyrine

CAS: 18125-49-0

Ref. TR-H805090

Product Information

• Name: 3-Hydroxymethylantipyrine
• Synonyms: 3-(Hydroxymethyl)-2-methyl-1-phenyl-3-pyrazolin-5-one, HMA, 1,2-Dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-3H-pyrazol-3-one, 3-(Hydroxymethyl)-2-methyl-1-phenyl-3-pyrazolin-5-one, Hydroxymethylantipyrine, 3-Hmap, 3-Pyrazolin-5-one, 3-(hydroxymethyl)-2-methyl-1-phenyl-, 3H-Pyrazol-3-one, 1,2-dihydro-5-(hydroxymethyl)-1-methyl-2-phenyl-, 5-(hydroxymethyl)-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one

Description

Applications Antipyrine (A697500), a non-steroidal anti-inflammatory drug, is widely utilized as a probe for human oxidative drug metabolism. Antipyrine metabolites are formed by various hepatic cytochrome P450 enzymes. 3-Hydroxymethylantipyrine is a metabolite of Antipyrine.
References Anadón A et al. Toxicol Lett. 2013 Jul 4;220(2):135-42Jorquera F et al. Dig Dis Sci. 2001 Feb;46(2):352-9Lehmann WD et al. Biomed Mass Spectrom. 1982 Nov;9(11):477-82.Engel G et al. Clin Pharmacol Ther. 1996 Jun;59(6):613-23.

• Brand: TRC

Chemical properties

• Molecular weight: 204.23
• Formula: C₁₁H₁₂N₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C11H12N2O2/c1-12-10(8-14)7-11(15)13(12)9-5-3-2-4-6-9/h2-7,14H,8H2,1H3
• InChI key: InChIKey=JBJKAGOWIZGVTR-UHFFFAOYSA-N
• SMILES: Cn1c(CO)cc(=O)n1-c1ccccc1