Hydroxocobalamin

CAS: 13422-51-0

Ref. TR-H862820

Product Information

• Name: Hydroxocobalamin
• Synonyms: Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-?N3), Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole, Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole, Alpha Cobione, AlphaRedisol, Axlon, Ciplamin H, Cobalamin, hydroxo-, Cobalex, Cobalin H, Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole inner salt, Codroxomin, Docclan, Docelan, Docevita, Droxomin, Ducobee Hy, Duradoce, Duralta-12, Hydrocobalamin, Hydrogrisevit, Hydrovit, Hydroxocobalamine, Hydroxocobemine, Hydroxy vitamin B12, Hydroxycobalamin, Hydroxycobalamine, Hyxobamine, Idrogrisevit, Megamilbedoce, Neo-Betalin 12, Neo-Cytamen, Neo-Macrabin, Neo-Rojamin, OH-Duphar, Oxobemin, Primabalt RP, Redisol H, Sytobex H, Vibeden, Vitadurin, Vitamin B12a, a-(5,6-Dimethylbenzimidazolyl)hydroxocobamide, Cobalamin, hydroxo-, Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole inner salt, Cobinamide hydroxide phosphate 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole inner salt, Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono (inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole, Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole, Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole, Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole, Cyanokit, Depovit B12, Hidroxocobalamina, Hydroxy vitamin B₁₂, Vitamin B_12a, α-(5,6-Dimethylbenzimidazolyl)hydroxocobamide

Description

Stability Hygroscopic
Applications Hydroxocobalamin is an intermediate in the synthesis of Nitritocobalamin(N490240) is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate (H826800); a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).
References Kaczka, E.A., et al.: Science, 112, 354 (1950); Friedrich, W., et al.: Vitamins, 837 (1988); Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993)

• Brand: TRC

Chemical properties

• Molecular weight: 1346.36
• Formula: C₆₂H₈₉CoN₁₃O₁₅P
• Purity: ~90%
• Color/Form: Dark Red To Purple
• InChI: InChI=1S/C62H90N13O14P.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56, , 1H2/q, , , /m1../s1, +3, /p-3/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+, /h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86)
• SMILES: CNC(=O)C[N+](=O)[O-]