5-Hydroxyindole

CAS: 1953-54-4

Ref. TR-H943510

Product Information

• Name: 5-Hydroxyindole
• Synonyms: 1H-Indol-5-ol, Indol-5-ol, 5-Hydroxy-1H-indole, NSC 87503, 1H-Indol-5-Ol, 5-Hydroxy-indole, 5-Indolol, Hydroxy-5 indole, Hydroxy-5Indole, Hydroxyindole, Indol-5-Ol, Timtec-Bb Sbb004214
• CAS: 1953-54-4

Description

Applications 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.
References Yamazaki, Y. et al.: Zeitsch. Naturforsch. C: J. Biosci., 65, 49 (2010); Kay, W.W. et al.: Gen. Pharmacol., 8, 201 (1977); Ghebregzabher, M. et al.: J. Chrom. Biomed. Appl., 222, 191 (1981);

• Brand: TRC

Chemical properties

• Molecular weight: 133.15
• Formula: C₈H₇NO
• Color/Form: Brown Solid
• InChI: InChI=1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
• InChI key: InChIKey=LMIQERWZRIFWNZ-UHFFFAOYSA-N
• SMILES: Oc1ccc2[nH]ccc2c1