(2R,3S)-beta-Hydroxyleucine

CAS: 87421-23-6

Ref. TR-H943740

Product Information

• Name: (2R,3S)-beta-Hydroxyleucine
• Synonyms: (2R,3S)-beta-Hydroxyleucine, D(-)-threo-3-Hydroxyleucine, (2R,3S)-2-amino-3-hydroxy-4-methylpentanoic acid (non-preferred name), D-Threo-Hydroxyleucine

Description

Applications (2R,3S)-β-Hydroxyleucine is a nonprotein amino acid. (2R,3S)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2R,3S)-β-Hydroxyleucine was effective in inhibiting trypsin and proteinase K of the serine proteases group. (2R,3S)-β-Hydroxyleucine was not able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2S,3R)-isomer.
References Hovhannisyan, N. et al.: Amino Acids, 37, 531 (2009); Chitchyan, M.B. et al.: Hayas. Kensab. Hand., 59, 248 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 147.172
• Formula: C₆H₁₃NO₃
• Color/Form: Neat
• InChI: InChI=1S/C6H13NO3/c1-3(2)5(8)4(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t4-,5+/m1/s1
• InChI key: InChIKey=ZAYJDMWJYCTABM-UHNVWZDZSA-N
• SMILES: CC(C)[C@H](O)[C@@H](N)C(=O)O