Estimated delivery in United States, on Monday 10 Feb 2025
Product Information
Name:
(S)-4-Hydroxymethyl Ambrisentan
Controlled Product
Synonyms:
- (alphaS)-alpha-[[4-(Hydroxymethyl)-6-methyl-2-pyrimidinyl]oxy]-beta-methoxy-beta-phenylbenzenepropanoic Acid
Description:
Applications (S)-4-Hydroxymethyl Ambrisentan is a metabolite of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996); Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002); Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
394.42
Formula:
C22H22N2O5
Color/Form:
Neat
InChI:
InChI=1S/C22H22N2O5/c1-15-13-18(14-25)24-21(23-15)29-19(20(26)27)22(28-2,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-13,19,25H,14H2,1-2H3,(H,26,27)/t19-/m1/s1
InChI key:
InChIKey=PDUAYPFMBRYSNN-LJQANCHMSA-N
SMILES:
COC(c1ccccc1)(c1ccccc1)[C@H](Oc1nc(C)cc(CO)n1)C(=O)O
MDL:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-H947760 (S)-4-Hydroxymethyl Ambrisentan
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