2-Hydroxy-2-phenyl-1H-indene-1,3(2H)-dione

CAS: 3761-46-4

Ref. TR-H949575

Product Information

• Name: 2-Hydroxy-2-phenyl-1H-indene-1,3(2H)-dione
• Synonyms: 1H-Indene-1,3(2H)-dione, 2-hydroxy-2-phenyl-, 1,3-Indandione, 2-hydroxy-2-phenyl- (7CI,8CI), 2-Hydroxy-2-phenylindan-1,3-dione

Description

Applications 2-Hydroxy-2-phenyl-1H-indene-1,3(2H)-dione is an impurity of phenindione (P297250), a proton pump inhibitor and traditional nonsteroidal anti-inflammatory drug used for acute interstitial nephritis and acute kidney injury.
References Haywood, P.A., et. al.: P. Anal. Div. Chem. Soc., 15, 332 (1978); Leonard, C.E., et al.: Pharmacoepidemiol. Drug. Safety., 21, 1155 (2012); Moda, T.L., et al.: Bioorg. Med. Chem. Lett., 22, 2889 (2012); Dhareshwar, S.S., et al.: J. Pharma. Sci., 99, 2711 (2010)

• Brand: TRC

Chemical properties

• Molecular weight: 238.24
• Formula: C₁₅H₁₀O₃
• Color/Form: Neat
• InChI: InChI=1S/C15H10O3/c16-13-11-8-4-5-9-12(11)14(17)15(13,18)10-6-2-1-3-7-10/h1-9,18H
• InChI key: InChIKey=LCRCBXLHWTVPEQ-UHFFFAOYSA-N
• SMILES: O=Cc1ccccc1-c1ccccc1