endo-alpha-Hydroxy-alpha-phenylbenzeneacetic Acid 8-Azabicyclo[3.2.1]oct-3-yl Ester Hydrochloride

CAS: 63516-30-3

Ref. TR-H950150

Product Information

• Name: endo-alpha-Hydroxy-alpha-phenylbenzeneacetic Acid 8-Azabicyclo[3.2.1]oct-3-yl Ester Hydrochloride
• Synonyms: Trospium Chloride USP Related Compound B, Trospium Chloride USP RC B,Trospium Chloride Imp. B (EP), Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1), Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, (3-endo)-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (9CI), Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride, endo-, Trospium Related Compound B as Hydrochloride, Trospium Chloride Impurity B as Hydrochloride, Trospium Impurity B as Hydrochloride

Description

Applications endo-α-Hydroxy-α-phenylbenzeneacetic Acid 8-Azabicyclo[3.2.1]oct-3-yl Ester Hydrochloride, is a derivative of Trospium Chloride (T892800), which is an Antispasmodic, used in treatment of urinary incontinence.
References Antweiler, H., et al.: Arzneim.-Forsch., 16, 1581 (1966), Lux, G., et al.: Fortschr. Med., 96, 2113 (1978), Madersbacher, H., et al.: Br. J. Urol., 75, 452 (1995), Zinner, N.R., et al.: Expert Opin. Pharmacother., 6, 1409 (2005),

• Brand: TRC

Chemical properties

• Molecular weight: 373.87
• Formula: C₂₁H₂₃NO₃·ClH
• Color/Form: Neat
• InChI: /h1-10,17-19,22,24H,11-14H2, InChI=1S/C21H23NO3.ClH/c23-20(25-19-13-17-11-12-18(14-19)22-17)21(24,15-7-3-1-4-8-15)16-9-5-2-6-10-16, 1H/t17-,18+,19+
• InChI key: InChIKey=VPKCUVMIEGXKID-DIXMHULASA-N
• SMILES: Cl.O=C(O[C@H]1C[C@@H]2CC[C@H](C1)N2)C(O)(c1ccccc1)c1ccccc1