Product Information
Name:
7-(2-Hydroxypropyl)guanine
Synonyms:
- 2-Amino-1,7-dihydro-7-(2-hydroxypropyl)-6H-purin-6-one
- N7-(2-Hydroxypropyl)guanine
- 2-Amino-7-(2-hydroxypropyl)-6,7-dihydro-1H-purin-6-one
- 6H-Purin-6-one, 2-amino-1,7-dihydro-7-(2-hydroxypropyl)-
- 7-(2-Hydroxypropyl)Guanine
- N<sup>7</sup>-(2-Hydroxypropyl)guanine
Description:
Applications A major adduct from alkylation of DNA by the genotoxic carcinogen, propylene oxide. Molecular dosimetry studies are used to find the amount present in tissues of F344 rats after inhalation exposure to propylene oxide
References Rios-Blanco, M.N. et al.: Carcinogen., 24, 1233 (2003); Segerback, D. et al.: Chem.-Biol. Inter., 115, 229 (1998);
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
209.21
Formula:
C8H11N5O2
Color/Form:
Pale Beige Solid
InChI:
InChI=1S/C8H11N5O2/c1-4(14)2-13-3-10-6-5(13)7(15)12-8(9)11-6/h3-4,14H,2H2,1H3,(H3,9,11,12,15)
InChI key:
InChIKey=JVWVMKYNORDKGP-UHFFFAOYSA-N
SMILES:
CC(O)Cn1cnc2[nH]c(N)nc(=O)c21
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