1-Hydroxy-2-(2-pyridinyl) Risedronate

CAS: 105462-23-5

Ref. TR-H952810

Product Information

• Name: 1-Hydroxy-2-(2-pyridinyl) Risedronate
• Synonyms: Risedronate Sodium 2.5 Hydrate Imp. B (EP), Risedronate Imp. B (EP), Risedronate USP Related Compound A, Risedronate USP RC A, Risedronate Sodium 2.5 Hydrate Imp B (Pharmeuropa), [1-Hydroxy-2-(pyridin-2-yl)ethane-1,1-diyl]bis(phosphonic Acid), P,P'-[1-Hydroxy-2-(2-pyridinyl)ethylidene]bis-phosphonic acid, [1-Hydroxy-2-(2-pyridinyl)ethylidene]bis-phosphonic acid, NE 58018, Risedronate Related Compound A, Risedronate Sodium 2.5 Hydrate Impurity B, Risedronate Impurity B, Phosphonicacid, [1-hydroxy-2-(2-pyridinyl)ethylidene]bis- (9CI), Ne 58018

Description

Applications 1-Hydroxy-2-(2-pyridinyl) Risedronate is an impurity in the synthesis of Risedronate (R521505), a pyridinyl biphosphonate bone resorption inhibitor.
References Mortensen, L., et al.: J. Clin. Endocrinol. Metab., 83, 396 (1998); Harris, S.T., et al.: J. Am. Med. Assoc., 282, 1344 (1999); Boiser, S., et al.: Cancer Res., 60, 2949 (2000)

• Brand: TRC

Chemical properties

• Molecular weight: 283.11
• Formula: C₇H₁₁NO₇P₂
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-3-1-2-4-8-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
• InChI key: InChIKey=WMKBUQPKAAJBHZ-UHFFFAOYSA-N
• SMILES: CN(C)CCc1c[nH]c2ccc(Cc3[nH]c4ccc(Cn5cncn5)cc4c3CCN(C)C)cc12