5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)
CAS: 504413-73-4
Ref. TR-H954455
1mg | 260.00 € | ||
10mg | 1,747.00 € |
Product Information
- 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- 10-[(dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-
- (4S)-
- (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
- 10-Hydroxy-9-[(dimethylamino)methyl]-5-hydroxy-(20S,5RS)-camptothecin
Stability Hygroscopic
Applications Dihydrochloride Salt of 5-Hydroxy Topotecan, is the metabolite of Topotecan (T542500), which is a DNA topoisomerase I inhibitor, semi synthetic analog of Camptothecin, and an antineoplastic.
References Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990), BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991), Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992),
Chemical properties
Technical inquiry about: TR-H954455 5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)
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